By car from Athens you need to cover 415 km. to get to Makrinitsa of Pelion. Either from Athens or Thessaloniki, take the exit of Highway to Volos - Velestino and just before you enter Volos you'll see the signs to Portaria. You will find yourself in the ring road of Volos. After the municipal stadium of the city turn with direction to Ano Volos and Portaria. From there you will only have to drive 2 km. to get to your destination.
Buses connect major cities (Athens, Thessaloniki, Patras, Ioannina, Kozani, Lamia, Larissa) to Volos, while there are daily train itineraries as well.
Bus Station Volos: +302421033253-4, +302421025527
Bus Station Athens: +302108329585
Bus Station Thessaloniki: +302310595424
Train Station Volos: +302421024056
Train Station Athens: +30210 5297777
Train Station Thessaloniki: +302310598114-5